(19)
(11) EP 0 462 179 A1

(12)

(43) Date of publication:
27.12.1991 Bulletin 1991/52

(21) Application number: 90904551.0

(22) Date of filing: 27.02.1990
(51) International Patent Classification (IPC): 
C07D 215/ 36( . )
A61K 31/ 19( . )
A61K 31/ 24( . )
A61K 31/ 44( . )
A61K 31/ 47( . )
C07C 311/ 21( . )
C07C 311/ 39( . )
C07C 317/ 34( . )
C07C 323/ 67( . )
C07D 213/ 81( . )
C07D 295/ 192( . )
A61K 31/ 18( . )
A61K 31/ 215( . )
A61K 31/ 40( . )
A61K 31/ 4427( . )
A61P 35/ 00( . )
C07C 311/ 37( . )
C07C 311/ 44( . )
C07C 323/ 49( . )
C07D 213/ 79( . )
C07D 295/ 135( . )
C07D 401/ 12( . )
(86) International application number:
PCT/US1990/001054
(87) International publication number:
WO 1990/009787 (07.09.1990 Gazette 1990/21)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB IT LI LU NL SE

(30) Priority: 27.02.1989 US 19890315837

(71) Applicant: THE DU PONT MERCK PHARMACEUTICAL COMPANY
Wilmington, Delaware 19805 (US)

(72) Inventors:
  • BEHRENS, Carl, Henry
    Wilmington, DE 19810 (US)
  • CHEN, Shih-Fong
    Swarthmore, PA 19081 (US)
  • JIANG, Jack, Bau, Chien
    Chapel Hill, NC 27514 (US)

(74) Representative: von Kreisler, Alek, Dipl.-Chem., et al 
Patentanwälte von Kreisler-Selting-Werner Postfach 10 22 41
D-50462 Köln
D-50462 Köln (DE)

   


(54) NOVEL SULFONAMIDES AS RADIOSENSITIZERS