(19)

(11)

EP 0 463 004 A1

(12)

(43) Date of publication: 02.01.1992 Bulletin 1992/01 (21) Application number: 90904185.0 (22) Date of filing: 06.03.1990

(51) International Patent Classification (IPC):  A61K 38/ 00( . ) A61P 3/ 02( . ) A61P 19/ 10( . ) A61K 38/ 20( . ) A61P 3/ 14( . ) A61P 43/ 00( . ) (86) International application number: PCT/AU1990/000092 (87) International publication number: WO 1990/010454 (20.09.1990 Gazette 1990/22)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB IT LI LU NL SE (30) Priority: 07.03.1989 AU 19890003091 15.06.1989 AU 19890004742 (71) Applicant: AMRAD CORPORATION LIMITED Kew, VIC 3101 (AU)	(72) Inventors: METCALF, Donald Balwyn, VIC 3103 (AU) REID, Ian Reginald Auckland 3 (NZ) MARTIN, Thomas John Kew, VIC 3101 (AU) (74) Representative: Grubb, Philip William  B.A. Yorke & Co. Coomb House 7 St. John's Road Isleworth Middlesex TW7 6NH Isleworth Middlesex TW7 6NH (GB)