(19)
(11) EP 0 463 037 A1

(12)

(43) Date of publication:
02.01.1992 Bulletin 1992/01

(21) Application number: 90904716.0

(22) Date of filing: 15.03.1990
(51) International Patent Classification (IPC): 
C12N 15/ 09( . )
A61K 38/ 21( . )
A61K 39/ 00( . )
A61K 39/ 395( . )
A61P 35/ 00( . )
A61P 43/ 00( . )
C07K 14/ 505( . )
C07K 14/ 53( . )
C07K 14/ 54( . )
C07K 14/ 55( . )
C07K 16/ 00( . )
C12N 15/ 12( . )
C12R 1/ 91( . )
A61K 38/ 00( . )
A61K 38/ 22( . )
A61K 39/ 39( . )
A61P 31/ 04( . )
A61P 37/ 04( . )
C07K 14/ 00( . )
C07K 14/ 52( . )
C07K 14/ 535( . )
C07K 14/ 545( . )
C07K 14/ 555( . )
C12N 5/ 10( . )
C12P 21/ 02( . )
(86) International application number:
PCT/US1990/001355
(87) International publication number:
WO 1990/011301 (04.10.1990 Gazette 1990/23)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB IT LI LU NL SE

(30) Priority: 17.03.1989 US 19890325408

(71) Applicants:
  • GENETICS INSTITUTE, INC.
    Cambridge, MA 02140 (US)
  • BRIGHAM AND WOMEN'S HOSPITAL
    Boston, Massachusetts 02115 (US)

(72) Inventors:
  • CLARK, Steven, C.
    Winchester, MA 01890 (US)
  • WEISER, Weishui
    Concord, MA 01742 (US)

(74) Representative: VOSSIUS & PARTNER 
Postfach 86 07 67
D-81634 München
D-81634 München (DE)

   


(54) HUMAN MACROPHAGE MIGRATION INHIBITORY FACTOR