(19)
(11)
EP 0 463 109 A1
(12)
(43)
Date of publication:
02.01.1992
Bulletin 1992/01
(21)
Application number:
90905932.0
(22)
Date of filing:
23.03.1990
(51)
International Patent Classification (IPC):
C07K
16/
40
( . )
C12N
15/
866
( . )
A61K
38/
00
( . )
C12N
9/
40
( . )
C12P
21/
08
( . )
A61K
48/
00
( . )
(86)
International application number:
PCT/US1990/001571
(87)
International publication number:
WO 1990/011353
(
04.10.1990
Gazette 1990/23)
(84)
Designated Contracting States:
AT BE CH DE DK ES FR GB IT LI LU NL SE
(30)
Priority:
24.03.1989
US 19890328421
(71)
Applicant:
RESEARCH CORPORATION TECHNOLOGIES, INC.
Tucson Arizona 85710-2815 (US)
(72)
Inventors:
CALHOUN, David, H.
Leonia, NJ 07605 (US)
COPPOLA, George
Hartsdale, NY 10530 (US)
(74)
Representative:
Kolb, Helga, Dr. Dipl.-Chem., et al
Hoffmann, Eitle & Partner, Patentanwälte, Postfach 81 04 20
D-81904 München
D-81904 München (DE)
(54)
RECOMBINANT ALPHA-GALACTOSIDASE, A THERAPY FOR FABRY DISEASE