1,4,10,13-TETRAOXA-7,16-DIAZACYCLOOCTADECANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE FOR THE REMOVAL OF TOXIC METAL IONS AND RADIOACTIVE ISOTOPES FROM THE LIVING ORGANISM - Patent 0463123

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EP 0 463 123 A1

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(43)	Date of publication:
	02.01.1992 Bulletin 1992/01

(21)	Application number: 90916523.0

(22)	Date of filing: 07.11.1990

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International Patent Classification (IPC):

A61K 31/ 395^{( . )}
A61P 39/ 02^{( . )}
C07D 273/ 00^{( . )}
C07F 3/ 02^{( . )}
C07F 15/ 02^{( . )}

A61K 33/ 06^{( . )}
A61P 43/ 00^{( . )}
C07D 273/ 08^{( . )}
C07F 3/ 04^{( . )}

(86)	International application number:
	PCT/HU1990/000070

(87)	International publication number:
	WO 1991/010655 (25.07.1991 Gazette 1991/17)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IT LI LU NL SE

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Priority:

16.01.1990 HU 19900000145

(71)	Applicants:
	ORSZAGOS "FREDERIC JOLIOT-CURIE" SUGARBIOLOGIA ES SUGAREGESZSEGUGYI KUTATO INTEZET H-1221 Budapest (HU) KOSSUTH, Lajos Tudomanyegyetem H-4010 Debrecen (HU)

(72)	Inventors:
	EMRI, József H-4032 Debrecen (HU) Györi, Béla H-4032 Debrecen (HU) KOVACS, Zoltán H-4600 Kisvárda (HU) BRÜCHER, Ernö H-4032 Debrecen (HU) SZTANYIK, László, B. H-1126 Budapest (HU) VARGA, László H-1024 Budapest (HU) KIRALY, Ödön H-1136 Budapest (HU) KANYAR, Béla H-1136 Budapest (HU)

(74)	Representative: Lord, Hilton David, et al
	MARKS & CLERK, 57-60 Lincoln's Inn Fields London WC2A 3LS London WC2A 3LS (GB)

(54)	1,4,10,13-TETRAOXA-7,16-DIAZACYCLOOCTADECANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE FOR THE REMOVAL OF TOXIC METAL IONS AND RADIOACTIVE ISOTOPES FROM THE LIVING ORGANISM