(19)
(11) EP 0 464 137 A1

(12)

(43) Date of publication:
08.01.1992 Bulletin 1992/02

(21) Application number: 90905787.0

(22) Date of filing: 16.03.1990
(51) International Patent Classification (IPC): 
A61K( . )
C12N( . )
A61K 31/ 52( . )
A61K 31/ 70( . )
A61K 31/ 7052( . )
A61K 31/ 708( . )
A61K 45/ 06( . )
A61P 43/ 00( . )
C07D 473/ 30( . )
C07H 19/ 00( . )
C07H 19/ 06( . )
C12N 7/ 00( . )
C12N 9/ 00( . )
C07H( . )
A61K 31/ 505( . )
A61K 31/ 522( . )
A61K 31/ 7042( . )
A61K 31/ 7076( . )
A61K 39/ 21( . )
A61P 31/ 12( . )
C07D 405/ 04( . )
C07D 473/ 34( . )
C07H 19/ 04( . )
C07H 19/ 16( . )
C12N 7/ 06( . )
C12N 15/ 00( . )
(86) International application number:
PCT/US1990/001424
(87) International publication number:
WO 1990/011081 (04.10.1990 Gazette 1990/23)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB IT LI LU NL SE

(30) Priority: 17.03.1989 US 19890324934
01.09.1989 US 19890401908

(71) Applicant: ONCOGEN LIMITED PARTNERSHIP
Seattle, WA 98121 (US)

(72) Inventors:
  • BRANKOVAN, Vera
    Seattle WA 98109-3911 (US)
  • WHITE, Richard, J.
    Cheshire, CT 06410 (US)

(74) Representative: Hirsch, Marc-Roger 
Cabinet Hirsch 34 rue de Bassano
F-75008 Paris
F-75008 Paris (FR)

   


(54) INHIBITION OF HIV USING SYNERGISTIC COMBINATIONS OF NUCLEOSIDE DERIVATIVES