(19)
(11)
EP 0 464 137 A1
(12)
(43)
Date of publication:
08.01.1992
Bulletin 1992/02
(21)
Application number:
90905787.0
(22)
Date of filing:
16.03.1990
(51)
International Patent Classification (IPC):
A61K
( . )
C12N
( . )
A61K
31/
52
( . )
A61K
31/
70
( . )
A61K
31/
7052
( . )
A61K
31/
708
( . )
A61K
45/
06
( . )
A61P
43/
00
( . )
C07D
473/
30
( . )
C07H
19/
00
( . )
C07H
19/
06
( . )
C12N
7/
00
( . )
C12N
9/
00
( . )
C07H
( . )
A61K
31/
505
( . )
A61K
31/
522
( . )
A61K
31/
7042
( . )
A61K
31/
7076
( . )
A61K
39/
21
( . )
A61P
31/
12
( . )
C07D
405/
04
( . )
C07D
473/
34
( . )
C07H
19/
04
( . )
C07H
19/
16
( . )
C12N
7/
06
( . )
C12N
15/
00
( . )
(86)
International application number:
PCT/US1990/001424
(87)
International publication number:
WO 1990/011081
(
04.10.1990
Gazette 1990/23)
(84)
Designated Contracting States:
AT BE CH DE DK ES FR GB IT LI LU NL SE
(30)
Priority:
17.03.1989
US 19890324934
01.09.1989
US 19890401908
(71)
Applicant:
ONCOGEN LIMITED PARTNERSHIP
Seattle, WA 98121 (US)
(72)
Inventors:
BRANKOVAN, Vera
Seattle WA 98109-3911 (US)
WHITE, Richard, J.
Cheshire, CT 06410 (US)
(74)
Representative:
Hirsch, Marc-Roger
Cabinet Hirsch 34 rue de Bassano
F-75008 Paris
F-75008 Paris (FR)
(54)
INHIBITION OF HIV USING SYNERGISTIC COMBINATIONS OF NUCLEOSIDE DERIVATIVES