(19)
(11)
EP 0 465 561 A1
(12)
(43)
Date of publication:
15.01.1992
Bulletin 1992/03
(21)
Application number:
90905860.0
(22)
Date of filing:
26.03.1990
(51)
International Patent Classification (IPC):
A61K
39/
112
( . )
C12N
1/
21
( . )
C12N
15/
74
( . )
A61P
31/
04
( . )
C12N
15/
00
( . )
C12R
1/
42
( . )
(86)
International application number:
PCT/US1990/001603
(87)
International publication number:
WO 1990/011688
(
18.10.1990
Gazette 1990/24)
(84)
Designated Contracting States:
AT BE CH DE DK ES FR GB IT LI LU NL SE
(30)
Priority:
31.03.1989
US 19890332285
(71)
Applicant:
WASHINGTON UNIVERSITY
St. Louis, Missouri 63130-4899 (US)
(72)
Inventor:
CURTISS III, Roy
St. Louis, MO 63112 (US)
(74)
Representative:
Goldin, Douglas Michael, et al
J.A. KEMP & CO. 14, South Square Gray's Inn
London WC1R 5LX
London WC1R 5LX (GB)
(54)
AVIRULENT MICROBES AND USES THEREFOR