(19)
(11) EP 0 465 561 A1

(12)

(43) Date of publication:
15.01.1992 Bulletin 1992/03

(21) Application number: 90905860.0

(22) Date of filing: 26.03.1990
(51) International Patent Classification (IPC): 
A61K 39/ 112( . )
C12N 1/ 21( . )
C12N 15/ 74( . )
A61P 31/ 04( . )
C12N 15/ 00( . )
C12R 1/ 42( . )
(86) International application number:
PCT/US1990/001603
(87) International publication number:
WO 1990/011688 (18.10.1990 Gazette 1990/24)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB IT LI LU NL SE

(30) Priority: 31.03.1989 US 19890332285

(71) Applicant: WASHINGTON UNIVERSITY
St. Louis, Missouri 63130-4899 (US)

(72) Inventor:
  • CURTISS III, Roy
    St. Louis, MO 63112 (US)

(74) Representative: Goldin, Douglas Michael, et al 
J.A. KEMP & CO. 14, South Square Gray's Inn
London WC1R 5LX
London WC1R 5LX (GB)

   


(54) AVIRULENT MICROBES AND USES THEREFOR