(19)
(11) EP 0 465 580 A1

(12)

(43) Date of publication:
15.01.1992 Bulletin 1992/03

(21) Application number: 90906019.0

(22) Date of filing: 28.03.1990
(51) International Patent Classification (IPC): 
A61K 9/ 08( . )
A61K 47/ 24( . )
A61K 9/ 00( . )
A61K 47/ 38( . )
(86) International application number:
PCT/US1990/001584
(87) International publication number:
WO 1990/011079 (04.10.1990 Gazette 1990/23)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB IT LI LU NL SE

(30) Priority: 29.03.1989 US 19890329924

(71) Applicant: ALCON LABORATORIES, INC.
Ft. Worth, TX 76134 (US)

(72) Inventors:
  • KE, Tai-Lee
    Grand Prairie, TX 75052 (US)
  • COOPER, Eugene, R.
    Crowley, TX 76036 (US)
  • HAGER, Douglas, F.
    Fort Worth TX 76109 (US)
  • KEISTER, Jamieson, Charles
    Crowley, TX 76036 (US)

(74) Representative: Woodcraft, David Charles, et al 
BROOKES & MARTIN High Holborn House 52/54 High Holborn
London, WC1V 6SE
London, WC1V 6SE (GB)

   


(54) USE OF MONOACYL PHOSPHOGLYCERIDES TO ENHANCE THE CORNEAL PENETRATION OF OPHTHALMIC DRUGS