(19)

(11)

EP 0 466 817 A1

(12)

(43) Date of publication: 22.01.1992 Bulletin 1992/04 (21) Application number: 90906567.0 (22) Date of filing: 04.04.1990

(51) International Patent Classification (IPC):  C12N 15/ 09( . ) A61K 38/ 00( . ) C07K 14/ 00( . ) C07K 14/ 73( . ) C12P 21/ 02( . ) A61K 36/ 18( . ) A61P 31/ 12( . ) C07K 14/ 415( . ) C07K 19/ 00( . ) C12R 1/ 19( . ) (86) International application number: PCT/US1990/001816 (87) International publication number: WO 1990/012097 (18.10.1990 Gazette 1990/24)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB IT LI LU NL SE (30) Priority: 04.04.1989 US 19890333184 (71) Applicant: GENELABS INCORPORATED Redwood City, CA 94063 (US)	(72) Inventors: PIATEK, Michael, Jr. Pleasanton, CA 94566 (US) CHOW, Teresa Portola Valley, CA 94025 (US) FRY, Kirk Palo Alto, CA 94303 (US) (74) Representative: Goldin, Douglas Michael  J.A. KEMP & CO. 14, South Square Gray's Inn London WC1R 5LX London WC1R 5LX (GB)