(19)
(11) EP 0 467 987 A1

(12)

(43) Date of publication:
29.01.1992 Bulletin 1992/05

(21) Application number: 90907737.0

(22) Date of filing: 26.04.1990
(51) International Patent Classification (IPC): 
A61K 38/ 48( . )
A61K 38/ 54( . )
C07K 14/ 00( . )
C07K 16/ 18( . )
C07K 19/ 00( . )
C12N 9/ 70( . )
C12N 15/ 09( . )
C12N 15/ 85( . )
A61K 38/ 00( . )
A61K 38/ 46( . )
A61P 7/ 02( . )
C07K 14/ 315( . )
C07K 16/ 40( . )
C12N 9/ 68( . )
C12N 9/ 99( . )
C12N 15/ 12( . )
C12N 15/ 866( . )
(86) International application number:
PCT/US1990/002296
(87) International publication number:
WO 1990/013640 (15.11.1990 Gazette 1990/26)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB IT LI LU NL SE

(30) Priority: 01.05.1989 US 19890345801

(71) Applicant: THE UNIVERSITY OF NOTRE DAME DU LAC
Notre Dame, Indiana 46556 (US)

(72) Inventors:
  • CASTELLINO, Francis, J.
    Granger, IN 46530 (US)
  • WHITEFLEET-SMITH, Joann, L.
    Danielson, CT 06239 (US)
  • ROSEN, Elliot, D.
    South Bend, IN 46617 (US)
  • McLINDEN, James, H.
    Mishawaka, IN 46545 (US)

(74) Representative: Brown, John David, et al 
FORRESTER & BOEHMERT Franz-Joseph-Strasse 38
D-80801 München
D-80801 München (DE)

   


(54) METHODS AND MATERIALS FOR EXPRESSION OF HUMAN PLASMINOGEN IN A EUKARYOTIC CELL SYSTEM