(19)

(11)

EP 0 473 707 A1

(12)

(43) Date of publication: 11.03.1992 Bulletin 1992/11 (21) Application number: 90909022.0 (22) Date of filing: 25.05.1990

(51) International Patent Classification (IPC):  C10C 3/ 00( . ) A61K 31/ 00( . ) A61K 31/ 7042( . ) A61K 47/ 12( . ) A61K 47/ 22( . ) A61P 31/ 00( . ) C07H 17/ 08( . ) D01F 9/ 155( . ) A61K 9/ 107( . ) A61K 31/ 70( . ) A61K 31/ 7048( . ) A61K 47/ 14( . ) A61K 47/ 44( . ) A61P 31/ 04( . ) C10C 3/ 06( . ) (86) International application number: PCT/US1990/003063 (87) International publication number: WO 1990/014094 (29.11.1990 Gazette 1990/27)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB IT LI LU NL SE (30) Priority: 26.05.1989 US 19890358283 (71) Applicant: ABBOTT LABORATORIES Abbott Park, Illinois 60064-3500 (US)	(72) Inventors: HUI, Ho-Wah Vernon Hills, IL 60061 (US) HSU, Chung-Chiang Libertyville, IL 60048 (US) CANNON, John, B. Grayslake, IL 60030 (US) LOVELL, Michael, W. Buffalo Grove, IL 60089 (US) (74) Representative: Modiano, Guido, Dr.-Ing., et al  Modiano & Associati S.r.l. Via Meravigli, 16 I-20123 Milano I-20123 Milano (IT)