(19)
(11) EP 0 473 716 A1

(12)

(43) Date of publication:
11.03.1992 Bulletin 1992/11

(21) Application number: 90909272.0

(22) Date of filing: 25.05.1990
(51) International Patent Classification (IPC): 
A01K 67/ 027( . )
A61P 5/ 00( . )
C07K 14/ 72( . )
C12N 15/ 09( . )
C12R 1/ 91( . )
A61K 38/ 00( . )
C07K 14/ 705( . )
C12N 5/ 10( . )
C12P 21/ 02( . )
(86) International application number:
PCT/US1990/003113
(87) International publication number:
WO 1990/014356 (29.11.1990 Gazette 1990/27)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB IT LI LU NL SE

(30) Priority: 26.05.1989 US 19890358696

(71) Applicant: THE SALK INSTITUTE FOR BIOLOGICAL STUDIES
La Jolla California 92038 (US)

(72) Inventors:
  • EVANS, Ronald, Mark
    La Jolla, CA 92037 (US)
  • HOLLENBERG, Stanley, Mark
    Del Mar, CA 92014 (US)
  • ORO, Anthony, Eugene
    San Diego, CA 92117 (US)
  • DAMM, Klaus
    D-8000 Münich (DE)
  • HEYMAN, Richard, Alan
    Encinitas, CA 92024 (US)

(74) Representative: UEXKÜLL & STOLBERG 
Patentanwälte Beselerstrasse 4
D-22607 Hamburg
D-22607 Hamburg (DE)

   


(54) DOMINANT NEGATIVE MEMBERS OF THE STEROID/THYROID SUPERFAMILY OF RECEPTORS