(19)

(11)

EP 0 473 764 A1

(12)

(43) Date of publication: 11.03.1992 Bulletin 1992/11 (21) Application number: 91906773.0 (22) Date of filing: 22.03.1991

(51) International Patent Classification (IPC):  A61K 51/ 00( . ) A61P 35/ 00( . ) C07F 5/ 00( . ) A61P 29/ 00( . ) C07D 309/ 40( . ) (86) International application number: PCT/GB1991/000441 (87) International publication number: WO 1991/014664 (03.10.1991 Gazette 1991/23)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IT LI LU NL SE (30) Priority: 23.03.1990 GB 19900006522 (71) Applicants: Hider, Robert Charles St. Osyth Essex CO16 8JL (GB) HUEHNS, Ernst Reinhard London NW9 9PL (GB) PORTER, John Brooke London N1 2QF (GB)	(72) Inventors: Hider, Robert Charles St. Osyth Essex CO16 8JL (GB) HUEHNS, Ernst Reinhard London NW9 9PL (GB) PORTER, John Brooke London N1 2QF (GB) (74) Representative: Stephenson, Gerald Frederick  Patents Department British Technology Ltd 101 Newington Causeway London SE1 6BU London SE1 6BU (GB)