(19)
(11) EP 0 476 071 A1

(12)

(43) Date of publication:
25.03.1992 Bulletin 1992/13

(21) Application number: 90913804.0

(22) Date of filing: 05.06.1990
(51) International Patent Classification (IPC): 
C07H 21/ 00( . )
C12N 15/ 09( . )
C07H 21/ 04( . )
C12Q 1/ 68( . )
(86) International application number:
PCT/US1990/003138
(87) International publication number:
WO 1990/015065 (13.12.1990 Gazette 1990/28)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB IT LI LU NL SE

(30) Priority: 05.06.1989 US 19890361045

(71) Applicant: GILEAD SCIENCES, INC.
Foster City California 94404 (US)

(72) Inventor:
  • FROEHLER, Brian, C.
    Belmont, CA 94002 (US)

(74) Representative: Goldin, Douglas Michael, et al 
J.A. KEMP & CO. 14, South Square Gray's Inn
London WC1R 5LX
London WC1R 5LX (GB)

   


(54) EXONUCLEASE-RESISTANT OLIGONUCLEOTIDES AND METHODS FOR PREPARING THE SAME