(19)

(11)

EP 0 484 411 A1

(12)

(43) Date of publication: 13.05.1992 Bulletin 1992/20 (21) Application number: 90911644.0 (22) Date of filing: 20.07.1990

(51) International Patent Classification (IPC):  C12N 15/ 09( . ) C07K 14/ 55( . ) C12N 15/ 70( . ) C07K 14/ 34( . ) C12N 15/ 67( . ) C12P 21/ 00( . ) (86) International application number: PCT/US1990/004113 (87) International publication number: WO 1991/001374 (07.02.1991 Gazette 1991/04)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB IT LI LU NL SE (30) Priority: 24.07.1989 US 19890384248 (71) Applicant: SERAGEN, INC. Hopkinton, MA 01748 (US)	(72) Inventor: GENBAUFFE, Frank Needham Heights, MA 02194 (US) (74) Representative: Sheard, Andrew Gregory, et al  Kilburn & Strode 30, John Street London WC1N 2DD London WC1N 2DD (GB)