(19)
(11) EP 0 484 416 A1

(12)

(43) Date of publication:
13.05.1992 Bulletin 1992/20

(21) Application number: 90911746.0

(22) Date of filing: 27.07.1990
(51) International Patent Classification (IPC): 
A61K 38/ 00( . )
A61P 9/ 10( . )
A61P 25/ 28( . )
C12N 1/ 21( . )
C12N 15/ 67( . )
A61K 38/ 17( . )
A61P 25/ 00( . )
C07K 14/ 52( . )
C12N 15/ 16( . )
C12N 15/ 85( . )
(86) International application number:
PCT/EP1990/001232
(87) International publication number:
WO 1991/002067 (21.02.1991 Gazette 1991/05)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB IT LI LU NL SE

(30) Priority: 27.07.1989 US 19890386546
20.07.1990 US 19900555006

(71) Applicant: Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
D-37073 Göttingen (DE)

(72) Inventors:
  • LINDHOLM, Dan, Bjarne
    D-8000 München 60 (DE)
  • THOENEN, Hans, Friedrich, Erwin
    D-8000 München 40 (DE)
  • HENGERER, Bastian
    D-8032 Grafelfing (DE)

(74) Representative: Patentanwälte Ruff, Beier, Schöndorf und Mütschele 
Neckarstrasse 50
D-70173 Stuttgart
D-70173 Stuttgart (DE)

   


(54) REGULATION OF NERVE GROWTH FACTOR SYNTHESIS IN THE CENTRAL NERVOUS SYSTEM