(19)

(11)

EP 0 485 380 A1

(12)

(43) Date of publication: 20.05.1992 Bulletin 1992/21 (21) Application number: 90902980.0 (22) Date of filing: 05.02.1990

(51) International Patent Classification (IPC):  A61K 41/ 00( . ) C07K 14/ 435( . ) C07K 16/ 10( . ) C12P 21/ 08( . ) C07K 1/ 00( . ) C07K 16/ 00( . ) C07K 16/ 18( . ) A61K 39/ 00( . ) (86) International application number: PCT/AU1990/000040 (87) International publication number: WO 1990/008782 (09.08.1990 Gazette 1990/19)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB IT LI LU NL SE (30) Priority: 03.02.1989 AU 19890002534 (71) Applicant: AGEN LIMITED Acacia Ridge Queensland 4110 (AU)	(72) Inventors: BUNDESEN, Peter, Gregory Fig Tree Pocket, QLD 4069 (AU) RYLATT, Dennis, Brian Bardon, QLD 4065 (AU) HILLYARD, Carmel, Judith Paddington, QLD 4064 (AU) (74) Representative: Collier, Jeremy Austin Grey, et al  J.A.KEMP & CO. 14 South Square Gray's Inn London WC1R 5LX London WC1R 5LX (GB)