(19)
(11) EP 0 485 497 A1

(12)

(43) Date of publication:
20.05.1992 Bulletin 1992/21

(21) Application number: 90912554.0

(22) Date of filing: 30.07.1990
(51) International Patent Classification (IPC): 
A61K 38/ 00( . )
A61P 37/ 04( . )
C07K 14/ 52( . )
C07K 14/ 55( . )
C12N 1/ 21( . )
C12P 21/ 02( . )
A61K 47/ 48( . )
C07K 14/ 00( . )
C07K 14/ 54( . )
C07K 19/ 00( . )
C12N 15/ 09( . )
C12R 1/ 19( . )
(86) International application number:
PCT/US1990/004258
(87) International publication number:
WO 1991/002000 (21.02.1991 Gazette 1991/05)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB IT LI LU NL SE

(30) Priority: 02.08.1989 US 19890388557

(71) Applicant: Seragen, Incorporated
Hopkinton, MA 01778 (US)

(72) Inventors:
  • GENBAUFFE, Francis, S., Jr.
    Needham Heights, MA 02194 (US)
  • AKIYOSHI, Donna, E.
    Northborough, MA 01532 (US)

(74) Representative: Sheard, Andrew Gregory, et al 
Kilburn & Strode 30, John Street
London WC1N 2DD
London WC1N 2DD (GB)

   


(54) IL-2 DELETION MUTANTS