SLOWLY DISSOCIATING (TIGHT BINDING) DOPAMINE, SEROTONIN OR NOREPINEPHRINE REUPTAKE INHIBITORS AS COCAINE, AMPHETAMINE AND PHENCYCLIDINE ANTAGONISTS - Patent 0485512

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EP 0 485 512 A1

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(43)	Date of publication:
	20.05.1992 Bulletin 1992/21

(21)	Application number: 90913049.0

(22)	Date of filing: 03.08.1990

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International Patent Classification (IPC):

A61K 31/ 495^{( . )}
A61P 25/ 30^{( . )}

A61P 25/ 00^{( . )}
C07D 295/ 08^{( . )}

(86)	International application number:
	PCT/US1990/004360

(87)	International publication number:
	WO 1991/001732 (21.02.1991 Gazette 1991/05)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB IT LI LU NL SE

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Priority:

03.08.1989 US 19890388866

(71)	Applicant: THE UNITED STATES OF AMERICA as represented by the Secretary UNITED STATES DEPARTMENT OF COMMERCE
	Washington, DC 20002 (US)

(72)	Inventors:
	ROTHMAN, Richard, B. Silver Spring, MD 20910 (US) PERT, Agu Gaithersburg, MD 20879 (US) RICE, Kenner, C. Bethesda, MD 20817 (US) GREIG, Nigel, Hamilton Silver Spring, MD 20906 (US) REID, Audrey, Alice Bethesda, MD 20814 (US) AKUNNE, Hyacinth, Charles, Chi Laurel, MD 20708 (US) MELE, Andre Kensington, MD 20895 (US) THURKAUF, Andrew Branford, CT 06405 (US)

(74)	Representative: Jump, Timothy John Simon, et al
	Venner Shipley & Co. 20 Little Britain London EC1A 7DH London EC1A 7DH (GB)

(54)	SLOWLY DISSOCIATING (TIGHT BINDING) DOPAMINE, SEROTONIN OR NOREPINEPHRINE REUPTAKE INHIBITORS AS COCAINE, AMPHETAMINE AND PHENCYCLIDINE ANTAGONISTS