(19)

(11)

EP 0 486 655 A1

(12)

(43) Date of publication: 27.05.1992 Bulletin 1992/22 (21) Application number: 91911068.0 (22) Date of filing: 10.06.1991

(51) International Patent Classification (IPC):  A61K 33/ 40( . ) (86) International application number: PCT/GB1991/000928 (87) International publication number: WO 1991/019504 (26.12.1991 Gazette 1991/29)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IT LI LU NL SE (30) Priority: 08.06.1990 GB 19900012839 (71) Applicant: GAINCORP LIMITED London EC4V 5BY (GB)	(72) Inventor: ZAIDI, Mone St. George's Hospital Medical School London SW17 0RE (GB) (74) Representative: Abrams, Michael John  HASELTINE LAKE & CO. Hazlitt House 28 Southampton Buildings Chancery Lane London WC2A 1AT London WC2A 1AT (GB)