(19)
(11) EP 0 487 593 A1

(12)

(43) Date of publication:
03.06.1992 Bulletin 1992/23

(21) Application number: 90912790.0

(22) Date of filing: 10.08.1990
(51) International Patent Classification (IPC): 
A61K 31/ 435( . )
C07D 498/ 18( . )
 A61P 37/ 06( . )
C07H 19/ 01( . )
(86) International application number:
PCT/GB1990/001262
(87) International publication number:
WO 1991/002736 (07.03.1991 Gazette 1991/06)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB IT LI LU NL SE

(30) Priority: 18.08.1989 GB 19890018927
09.10.1989 GB 19890022653
04.06.1990 GB 19900012426

(71) Applicants:
  • FISONS plc
    Ipswich Suffolk IP1 1QH (GB)
  • FUJISAWA PHARMACEUTICAL CO., LTD.
    Osaka-shi Osaka 541 (JP)

(72) Inventors:
  • DONALD, David, Keith
    Ashby de la Zouch eicestershire LE6 5FE (GB)
  • HARDERN, David, Norman
    Loughborough Leicestershire LE12 5NP (GB)
  • COOPER, Martin, Edward
    Leicestershire LE11 0FE (GB)
  • FURBER, Mark
    Derby DE7 2EN (GB)
  • HASHIMOTO, Masashi
    Hyogo 665 (JP)
  • KASAHARA, Chiyoshi
    Osaka 563 (JP)
  • OHKAWA, Takehiko
    Ibaraki 305 (JP)

(74) Representative: Wright, Robert Gordon McRae 
FISONS plc 12 Derby Road
Loughborough Leicestershire LE11 0BB
Loughborough Leicestershire LE11 0BB (GB)

   


(54) MACROCYCLIC COMPOUNDS