(19)

(11)

EP 0 487 661 A1

(12)

(43) Date of publication: 03.06.1992 Bulletin 1992/23 (21) Application number: 91908277.0 (22) Date of filing: 22.04.1991

(51) International Patent Classification (IPC):  A61L 27/ 00( . ) C08F 2/ 52( . ) C12N 5/ 00( . ) A61L 27/ 34( . ) C08J 7/ 12( . ) (86) International application number: PCT/AU1991/000149 (87) International publication number: WO 1991/016378 (31.10.1991 Gazette 1991/25)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IT LI LU NL SE (30) Priority: 20.04.1990 AU 19900009738 (71) Applicant: COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION Campbell, Australian Capital Territory 2601 (AU)	(72) Inventors: CHATELIER, Ronald, Christopher Ringwood, VIC 3134 (AU) GRIESSER, Hans, Jorg The Patch, VIC 3792 (AU) STEELE, John, G. North Rocks, NSW 2151 (AU) JOHNSON, Graham Peakhurst, NSW 2210 (AU) (74) Representative: Wharton, Peter Robert  Urquhart-Dykes & Lord Inventions House Valley Court, Canal Road Bradford BD1 4SP Bradford BD1 4SP (GB)