(19)
(11) EP 0 493 533 A1

(12)

(43) Date of publication:
08.07.1992 Bulletin 1992/28

(21) Application number: 90917627.0

(22) Date of filing: 26.10.1990
(51) International Patent Classification (IPC): 
A61K 31/ 70( . )
C12N 9/ 26( . )
C07K 16/ 18( . )
(86) International application number:
PCT/US1990/006189
(87) International publication number:
WO 1991/006303 (16.05.1991 Gazette 1991/11)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB IT LI LU NL SE

(30) Priority: 27.10.1989 US 19890428374

(71) Applicants:
  • Case Western Reserve University
    Cleveland Ohio 44106 (US)
  • GLIATECH, INC.
    Beachwood, OH 44122 (US)

(72) Inventors:
  • SNOW, Diane, M.
    Fridley, MN 55432 (US)
  • SILVER, Jerry
    Lyndhurst, OH 44124 (US)
  • HAREL, Adrian
    Woodmere, OH 44122 (US)
  • ROUFA, Dikla
    St. Louis, MO 63146 (US)

(74) Representative: Hirsch, Marc-Roger 
Cabinet Hirsch 34 rue de Bassano
F-75008 Paris
F-75008 Paris (FR)

   


(54) INHIBITION OF CELL GROWTH BY KERATAN SULFATE, CHONDROITIN SULFATE, DERMATAN SULFATE AND OTHER GLYCANS