(19)
(11)
EP 0 496 746 A1
(12)
(43)
Date of publication:
05.08.1992
Bulletin 1992/32
(21)
Application number:
90914801.0
(22)
Date of filing:
10.10.1990
(51)
International Patent Classification (IPC):
A61K
31/
505
( . )
A61P
11/
00
( . )
A61P
25/
00
( . )
C07D
213/
74
( . )
C07D
239/
49
( . )
A61P
9/
00
( . )
A61P
17/
00
( . )
A61P
25/
28
( . )
C07D
239/
42
( . )
C07D
239/
50
( . )
(86)
International application number:
PCT/US1990/005645
(87)
International publication number:
WO 1991/006542
(
16.05.1991
Gazette 1991/11)
(84)
Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE
(30)
Priority:
25.10.1989
US 19890427143
(71)
Applicant:
THE UPJOHN COMPANY
Kalamazoo, MI 49001 (US)
(72)
Inventor:
AYER, Donald, E.
Kalamazoo, MI 49007 (US)
(74)
Representative:
Perry, Robert Edward, et al
GILL JENNINGS & EVERY Broadgate House 7 Eldon Street
London EC2M 7LH
London EC2M 7LH (GB)
(54)
PHARMACEUTICALLY ACTIVE AMINO-SUBSTITUTED HETEROARYL AMINES