(19)
(11) EP 0 496 746 A1

(12)

(43) Date of publication:
05.08.1992 Bulletin 1992/32

(21) Application number: 90914801.0

(22) Date of filing: 10.10.1990
(51) International Patent Classification (IPC): 
A61K 31/ 505( . )
A61P 11/ 00( . )
A61P 25/ 00( . )
C07D 213/ 74( . )
C07D 239/ 49( . )
A61P 9/ 00( . )
A61P 17/ 00( . )
A61P 25/ 28( . )
C07D 239/ 42( . )
C07D 239/ 50( . )
(86) International application number:
PCT/US1990/005645
(87) International publication number:
WO 1991/006542 (16.05.1991 Gazette 1991/11)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE

(30) Priority: 25.10.1989 US 19890427143

(71) Applicant: THE UPJOHN COMPANY
Kalamazoo, MI 49001 (US)

(72) Inventor:
  • AYER, Donald, E.
    Kalamazoo, MI 49007 (US)

(74) Representative: Perry, Robert Edward, et al 
GILL JENNINGS & EVERY Broadgate House 7 Eldon Street
London EC2M 7LH
London EC2M 7LH (GB)

   


(54) PHARMACEUTICALLY ACTIVE AMINO-SUBSTITUTED HETEROARYL AMINES