(19)
(11) EP 0 496 820 A1

(12)

(43) Date of publication:
05.08.1992 Bulletin 1992/32

(21) Application number: 90916631.0

(22) Date of filing: 15.10.1990
(51) International Patent Classification (IPC): 
C12N 1/ 19( . )
C12N 9/ 10( . )
C12N 15/ 82( . )
C12Q 1/ 02( . )
G01N 33/ 68( . )
C12N 1/ 21( . )
C12N 15/ 54( . )
C12P 21/ 00( . )
C12Q 1/ 48( . )
C12R 1/ 865( . )
(86) International application number:
PCT/US1990/005883
(87) International publication number:
WO 1991/006673 (16.05.1991 Gazette 1991/11)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE

(30) Priority: 25.10.1989 US 19890426381

(71) Applicant: THE GENERAL HOSPITAL CORPORATION
Boston, MA 02114 (US)

(72) Inventors:
  • SMITH, John, A.
    Brookline, MA 02146 (US)
  • LEE, Fang-Jen, S.
    Somerville, MA 02144 (US)

(74) Representative: Fischer, Hans-Jürgen, Dr. 
Hoechst AG Patent- und Lizenzabteilung Gebäude K 801
D-65926 Frankfurt am Main
D-65926 Frankfurt am Main (DE)

   


(54) ISOLATING OF STRAINS OF $i(SACCHAROMYCES CEREVISIAE) HAVING ALTERED N?$g(a) -ACETYLTRANSFERASE ACTIVITY