(19)
(11) EP 0 496 833 A1

(12)

(43) Date of publication:
05.08.1992 Bulletin 1992/32

(21) Application number: 90917700.0

(22) Date of filing: 18.10.1990
(51) International Patent Classification (IPC): 
A61K 38/ 00( . )
A61P 7/ 00( . )
C07K 14/ 495( . )
C12N 15/ 09( . )
C12R 1/ 19( . )
A61K 38/ 22( . )
A61P 43/ 00( . )
C07K 14/ 52( . )
C12P 21/ 02( . )
(86) International application number:
PCT/US1990/006006
(87) International publication number:
WO 1991/005565 (02.05.1991 Gazette 1991/10)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE

(30) Priority: 18.10.1989 US 19890422962

(71) Applicant: CREATIVE BIOMOLECULES, INC.
Hopkinton Massachusetts 01478 (US)

(72) Inventor:
  • COHEN, Charles, M.
    Medway, MA 02053 (US)

(74) Representative: Holdcroft, James Gerald, Dr., et al 
Graham Watt & Co., Riverhead
Sevenoaks, Kent TN13 2BN
Sevenoaks, Kent TN13 2BN (GB)

   


(54) BIOSYNTHETIC CONSTRUCTS OF TGF-$g(b)