(19)
(11) EP 0 497 833 A1

(12)

(43) Date of publication:
12.08.1992 Bulletin 1992/33

(21) Application number: 90915919.0

(22) Date of filing: 22.10.1990
(51) International Patent Classification (IPC): 
A61K 38/ 48( . )
A61P 31/ 04( . )
C07K 14/ 81( . )
C12P 21/ 02( . )
C12R 1/ 91( . )
A61K 38/ 55( . )
C07K 14/ 00( . )
C12N 15/ 15( . )
A61K 38/ 00( . )
(86) International application number:
PCT/US1990/006072
(87) International publication number:
WO 1991/006650 (16.05.1991 Gazette 1991/11)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE

(30) Priority: 27.10.1989 US 19890428202

(71) Applicant: CETUS CORPORATION
Emeryville California 94608 (US)

(72) Inventors:
  • ELDERING, Eric
    NL-Amsterdam (NL)
  • AARDEN, Lucien
    NL-Amsterdam (NL)

(74) Representative: Bizley, Richard Edward 
Hepworth, Lawrence, Bryer & Bizley Merlin House Falconry Court Bakers Lane
Epping Essex CM16 5DQ
Epping Essex CM16 5DQ (GB)

   


(54) C1 INHIBITOR MUTEINS AND USES THEREOF