PRODUCTION OF MULTIMERIC GLYCOPROTEINS THROUGH CHEMICAL COUPLING - Patent 0502131

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EP 0 502 131 A1

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(43)	Date of publication:
	09.09.1992 Bulletin 1992/37

(21)	Application number: 91909635.0

(22)	Date of filing: 03.05.1991

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International Patent Classification (IPC):

C07K 1/ 10^{( . )}
C07K 14/ 705^{( . )}
A61K 38/ 00^{( . )}

C07K 1/ 107^{( . )}
C07K 14/ 73^{( . )}

(86)	International application number:
	PCT/US1991/003080

(87)	International publication number:
	WO 1992/005188 (02.04.1992 Gazette 1992/08)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IT LI LU NL SE

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Priority:

14.09.1990 US 19900583022

(71)	Applicant: BIOGEN, INC.
	Cambridge Massachusetts 02142 (US)

(72)	Inventors:
	PEPINSKY, R., Blake Watertown, MA 02172 (US) ROSA, Joseph, J. Winchester, MA 01890 (US) CHEN, Ling-Ling Wellesley, MA 02181 (US)

(74)	Representative: VOSSIUS & PARTNER
	Postfach 86 07 67 D-81634 München D-81634 München (DE)

(54)	PRODUCTION OF MULTIMERIC GLYCOPROTEINS THROUGH CHEMICAL COUPLING