(19)

(11)

EP 0 504 305 A1

(12)

(43) Date of publication: 23.09.1992 Bulletin 1992/39 (21) Application number: 91902228.0 (22) Date of filing: 07.12.1990

(51) International Patent Classification (IPC):  A61K 39/ 395( . ) G01N 33/ 577( . ) G01N 33/ 53( . ) G01N 33/ 68( . ) (86) International application number: PCT/US1990/007239 (87) International publication number: WO 1991/009311 (27.06.1991 Gazette 1991/14)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IT LI LU NL SE (30) Priority: 08.12.1989 US 19890448117 (71) Applicant: SENETEK PLC St Louis, MO 63141 (US)	(72) Inventor: COPPARD, Nicholas, J. Luton Bedfordshire LU2 7JY (GB) (74) Representative: Allard, Susan Joyce, et al  BOULT, WADE & TENNANT 27 Furnival Street London EC4A 1PQ London EC4A 1PQ (GB)