(19)
(11) EP 0 506 893 A1

(12)

(43) Date of publication:
07.10.1992 Bulletin 1992/41

(21) Application number: 91905252.0

(22) Date of filing: 31.12.1990
(51) International Patent Classification (IPC): 
A61K 39/ 00( . )
C07K 14/ 725( . )
C12N 15/ 09( . )
G01N 33/ 50( . )
G01N 33/ 564( . )
A61K 38/ 00( . )
C07H 21/ 04( . )
C07K 16/ 28( . )
C12Q 1/ 68( . )
G01N 33/ 53( . )
G01N 33/ 577( . )
(86) International application number:
PCT/US1990/007699
(87) International publication number:
WO 1991/009623 (11.07.1991 Gazette 1991/15)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE

(30) Priority: 29.12.1989 US 19890459065
01.05.1990 US 19900517380

(71) Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Pasadena California 91125 (US)

(72) Inventors:
  • URBAN, James, L.
    Pasadena, CA 91104 (US)
  • ZALLER, Dennis, M.
    Pasadena, CA 91101 (US)
  • HOOD, Leroy, E.
    Pasadena, CA 91106 (US)
  • BEALL, Stevens, S.
    Pasadena, CA 91104 (US)
  • CONCANNON, Patrick
    Seattle, WA 98101 (US)

(74) Representative: Hirsch, Marc-Roger, et al 
Cabinet Hirsch 34 rue de Bassano
F-75008 Paris
F-75008 Paris (FR)

   


(54) DIAGNOSIS AND TREATMENT OF DISEASES