(19)
(11) EP 0 506 944 A1

(12)

(43) Date of publication:
07.10.1992 Bulletin 1992/41

(21) Application number: 91920615.0

(22) Date of filing: 21.10.1991
(51) International Patent Classification (IPC): 
C07K 1/ 107( . )
C12Q 1/ 68( . )
C12N 15/ 10( . )
(86) International application number:
PCT/US1991/007622
(87) International publication number:
WO 1992/006985 (30.04.1992 Gazette 1992/10)
(84) Designated Contracting States:
GB

(30) Priority: 23.10.1990 US 19900598665

(71) Applicant: CITY OF HOPE
Duarte California 91010-0269 (US)

(72) Inventors:
  • SMITH, Steven, S.
    Los Angeles, CA 90042 (US)
  • KAPLAN, Bruce, E.
    Claremont, CA 91711 (US)

(74) Representative: Sheard, Andrew Gregory 
Kilburn & Strode 30, John Street
London WC1N 2DD
London WC1N 2DD (GB)

   


(54) MECHANISM BASED INHIBITORS OF DNA METHYLTRANSFERASE