(19)
(11) EP 0 506 963 A1

(12)

(43) Date of publication:
07.10.1992 Bulletin 1992/41

(21) Application number: 91900328.0

(22) Date of filing: 18.12.1990
(51) International Patent Classification (IPC): 
C12N 1/ 21( . )
C07K 14/ 50( . )
C12N 15/ 16( . )
C12N 15/ 67( . )
C12P 21/ 02( . )
C12R 1/ 19( . )
 C07K 1/ 16( . )
C12N 15/ 09( . )
C12N 15/ 18( . )
C12N 15/ 70( . )
A61K 38/ 00( . )
(86) International application number:
PCT/JP1990/001646
(87) International publication number:
WO 1991/009126 (27.06.1991 Gazette 1991/14)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE

(30) Priority: 19.12.1989 JP 19890330225

(71) Applicant: Takeda Chemical Industries, Ltd.
Chuo-ku, Osaka (JP)

(72) Inventors:
  • KITANO, Kazuaki
    Osaka 590-01 (JP)
  • KURIYAMA, Masato
    Osaka-shi Osaka 534 (JP)
  • NISHIMURA, Osamu
    Hyogo 666-01 (JP)
  • IGARASHI, Koichi
    Kyoto-shi Kyoto 606 (JP)

(74) Representative: von Kreisler, Alek, Dipl.-Chem. 
Patentanwälte von Kreisler-Selting-Werner Postfach 10 22 41
D-50462 Köln
D-50462 Köln (DE)

   


(54) PRODUCTION OF HUMAN BASIC FGF MUTEIN