(19)

(11)

EP 0 507 872 A1

(12)

(43) Date of publication: 14.10.1992 Bulletin 1992/42 (21) Application number: 91902936.0 (22) Date of filing: 28.12.1990

(51) International Patent Classification (IPC):  A23L 1/ 29( . ) A61K 31/ 195( . ) A61K 31/ 405( . ) A61P 31/ 12( . ) A23L 1/ 305( . ) A61K 31/ 198( . ) A61K 31/ 415( . ) A61P 37/ 00( . ) (86) International application number: PCT/US1990/007689 (87) International publication number: WO 1991/009524 (11.07.1991 Gazette 1991/15)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IT LI LU NL SE (30) Priority: 29.12.1989 US 19890458996 (71) Applicant: McGAW, Inc. Irvine California 92714 (US)

(72) Inventors: YOSHIMURA, Norman, Nobuo Westminster, CA 92683 (US) BARBUL, Adrian Baltimore, MD 21217 (US) TAO, Robert, Chimei Huntington Beach, CA 92646 (US) STORM, Michael, Craig Laguna Niguel, CA 92677 (US) KELLY, Robert, Edward Orange, CA 92668 (US) REIS, Brenda, Leah Costa Mesa, CA 92627 (US) (74) Representative: Patentanwälte Grünecker, Kinkeldey, Stockmair & Partner  Maximilianstrasse 58 D-80538 München D-80538 München (DE)