(19)
(11)
EP 0 507 948 A1
(12)
(43)
Date of publication:
14.10.1992
Bulletin 1992/42
(21)
Application number:
91901637.0
(22)
Date of filing:
27.12.1990
(51)
International Patent Classification (IPC):
A61K
39/
395
( . )
C07K
14/
00
( . )
C07K
16/
00
( . )
C12N
5/
10
( . )
C12N
15/
02
( . )
C12N
15/
09
( . )
C12P
21/
02
( . )
G01N
33/
53
( . )
A61K
38/
00
( . )
C12R
1/
91
( . )
A61P
35/
00
( . )
C07K
14/
50
( . )
C07K
16/
22
( . )
C12N
5/
20
( . )
C12N
15/
06
( . )
C12N
15/
18
( . )
C12P
21/
08
( . )
G01N
33/
577
( . )
C12R
1/
19
( . )
(86)
International application number:
PCT/JP1990/001726
(87)
International publication number:
WO 1991/009875
(
11.07.1991
Gazette 1991/15)
(84)
Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE
(30)
Priority:
28.12.1989
JP 19890338369
29.06.1990
JP 19900169707
(71)
Applicant:
TAKEDA CHEMICAL INDUSTRIES, LTD.
Chuo-ku, Osaka 541 (JP)
(72)
Inventors:
KOZAI, Yoshio
Osaka 560 (JP)
HORI, Akira
Hyogo 663 (JP)
ICHIMORI, Yuzo
Osaka 592 (JP)
(74)
Representative:
von Kreisler, Alek, Dipl.-Chem., et al
Patentanwälte von Kreisler-Selting-Werner Postfach 10 22 41
D-50462 Köln
D-50462 Köln (DE)
(54)
MONOCLONAL ANTIBODY, HYBRIDOMAS, THEIR PRODUCTION AND USE