(19)
(11) EP 0 508 983 A1

(12)

(43) Date of publication:
21.10.1992 Bulletin 1992/43

(21) Application number: 90908325.0

(22) Date of filing: 17.05.1990
(51) International Patent Classification (IPC): 
A61K 38/ 00( . )
A61P 35/ 00( . )
C07K 14/ 00( . )
C07K 14/ 52( . )
C07K 16/ 22( . )
C12N 1/ 21( . )
C12P 21/ 08( . )
G01N 33/ 574( . )
C12R 1/ 19( . )
 A61K 39/ 395( . )
C07K 7/ 08( . )
C07K 14/ 495( . )
C07K 16/ 00( . )
C12N 1/ 11( . )
C12P 21/ 02( . )
G01N 33/ 53( . )
G01N 33/ 577( . )
C12R 1/ 91( . )
(86) International application number:
PCT/US1990/002753
(87) International publication number:
WO 1990/014360 (29.11.1990 Gazette 1990/27)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB IT LI LU NL SE

(30) Priority: 17.05.1989 US 19890353410

(71) Applicant: Oncogene Science, Inc.
Manhasset New York 11030 (US)

(72) Inventors:
  • IWATA, Kenneth, K.
    Westbury, NY 11590 (US)
  • STEPHENSON, John, R.
    Rockville Center, NY 11570 (US)
  • TEN DIJKE, Peter
    Port Washington, NY 11050 (US)
  • FRANCO, Robert
    Spencerport, NY 14559 (US)
  • GOLD, Leslie, I.
    New York, NY 10017 (US)
  • FOULKES, J., Gordon
    Huntington Station, NY 11746 (US)

(74) Representative: Henkel, Feiler, Hänzel & Partner 
Möhlstrasse 37
D-81675 München
D-81675 München (DE)

   


(54) TISSUE-DERIVED TUMOR GROWTH INHIBITORS, METHODS OF PREPARATION AND USES THEREOF