TARGET-SPECIFIC, CYTOTOXIC, RECOMBINANT PSEUDOMONAS EXOTOXIN - Patent 0509056

(19)

(11)

EP 0 509 056 A1

(12)

(43)	Date of publication:
	21.10.1992 Bulletin 1992/43

(21)	Application number: 91904103.0

(22)	Date of filing: 27.12.1990

(51)

International Patent Classification (IPC):

A61K 38/ 00^{( . )}
C07K 14/ 00^{( . )}
C07K 14/ 495^{( . )}
C07K 16/ 28^{( . )}
C12N 15/ 09^{( . )}
C12P 21/ 02^{( . )}
C12R 1/ 38^{( . )}

A61P 35/ 00^{( . )}
C07K 14/ 21^{( . )}
C07K 14/ 73^{( . )}
C07K 19/ 00^{( . )}
C12N 15/ 31^{( . )}
C12R 1/ 19^{( . )}

(86)	International application number:
	PCT/US1990/007421

(87)	International publication number:
	WO 1991/009949 (11.07.1991 Gazette 1991/15)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IT LI LU NL SE

(30)

Priority:

02.01.1990 US 19900459635

(71)	Applicant: THE UNITED STATES OF AMERICA, represented by THE SECRETARY, UNITED STATES DEPARTMENT OF COMMERCE
	Washington, DC 20231 (US)

(72)	Inventors:
	PASTAN, Ira Potomac, MD 20854 (US) CHAUDHARY, Vijay Rockville, MD 20852 (US) FITZGERALD, David Silver Spring, MD 20902 (US)

(74)	Representative: Wain, Christopher Paul, et al
	A.A. THORNTON & CO. Northumberland House 303-306 High Holborn London WC1V 7LE London WC1V 7LE (GB)

(54)	TARGET-SPECIFIC, CYTOTOXIC, RECOMBINANT PSEUDOMONAS EXOTOXIN