(19)
(11)
EP 0 511 285 A1
(12)
(43)
Date of publication:
04.11.1992
Bulletin 1992/45
(21)
Application number:
91903122.0
(22)
Date of filing:
16.01.1991
(51)
International Patent Classification (IPC):
A61K
48/
00
( . )
C07K
14/
16
( . )
C12N
15/
09
( . )
C12N
15/
867
( . )
C12R
1/
91
( . )
A61P
31/
12
( . )
C12N
5/
10
( . )
C12N
15/
113
( . )
A61K
38/
00
( . )
C12R
1/
92
( . )
(86)
International application number:
PCT/US1991/000175
(87)
International publication number:
WO 1991/010453
(
25.07.1991
Gazette 1991/17)
(84)
Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE
(30)
Priority:
18.01.1990
US 19900467407
15.10.1990
US 19900596299
(71)
Applicant:
THE UNITED STATES OF AMERICA, represented by THE SECRETARY, UNITED STATES DEPARTMENT OF COMMERCE
Washington, DC 20231 (US)
(72)
Inventor:
LISZIEWICZ, Julianna
Bethesda, MD 20817 (US)
(74)
Representative:
Eyles, Christopher Thomas
W.P. THOMPSON & CO. Celcon House 289-293 High Holborn
London WC1V 7HU
London WC1V 7HU (GB)
(54)
VECTOR WITH MULTIPLE TARGET RESPONSE ELEMENTS AFFECTING GENE EXPRESSION