(19)
(11) EP 0 512 104 A1

(12)

(43) Date of publication:
11.11.1992 Bulletin 1992/46

(21) Application number: 92900692.0

(22) Date of filing: 01.11.1991
(51) International Patent Classification (IPC): 
A61K 8/ 49( . )
A61K 31/ 505( . )
A61K 47/ 44( . )
A61K 9/ 00( . )
A61K 47/ 26( . )
A61Q 11/ 00( . )
(86) International application number:
PCT/US1991/008092
(87) International publication number:
WO 1992/009283 (11.06.1992 Gazette 1992/13)
(84) Designated Contracting States:
AT BE CH DE ES FR GB GR IT LI NL SE

(30) Priority: 26.11.1990 US 19900617729

(71) Applicant: WARNER-LAMBERT COMPANY
Morris Plains New Jersey 07950 (US)

(72) Inventors:
  • CARLIN, Edward, J.
    Secaucus, NJ 07094 (US)
  • TALWAR, Anil, K.
    Long Valley, NJ 07853 (US)
  • DILLS, Steven, S.
    Hackettstown, NJ 07874 (US)
  • TALMAGE, Joseph, M.
    Landing, NJ 07853 (US)
  • SAMARCO, Eugène, C.
    Andover, NJ 07821 (US)

(74) Representative: Silbiger, Jakob, Dr. 
c/o CAPSUGEL AG Fabrikmattenweg 2-4
CH-4144 Arlesheim
CH-4144 Arlesheim (CH)

   


(54) STABILIZED HEXAHYDRO-5-PYRIMIDINAMINE COMPOUNDS IN AQUEOUS SOLUTION AND METHODS FOR PREPARING SAME