BRANCHED ALKYL ESTERS OF 4-BIS (CHLOROETHYL) AMINOPHENYL-ALKYL CARBOXYLIC ACIDS FOR TREATMENT OF PRIMARY AND METASTATIC TUMORS OF THE LYMPHATIC SYSTEM, AND OF CANCERS OF THE BREAST AND OVARIES - Patent 0514437

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EP 0 514 437 A1

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(43)	Date of publication:
	25.11.1992 Bulletin 1992/48

(21)	Application number: 91903814.0

(22)	Date of filing: 08.02.1991

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International Patent Classification (IPC):

A61K 31/ 215^{( . )}

(86)	International application number:
	PCT/US1991/000763

(87)	International publication number:
	WO 1991/011998 (22.08.1991 Gazette 1991/19)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IT LI LU NL SE

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Priority:

09.02.1990 US 19900478075

(71)	Applicant: THE UNITED STATES OF AMERICA, represented by THE SECRETARY, UNITED STATES DEPARTMENT OF COMMERCE
	Washington, DC 20231 (US)

(72)	Inventors:
	GREIG, Nigel, H. Silver Spring, MD 20906 (US) GENKA, Shigeru Setagaya-ku, Tokyo 158 (JP) SONCRANT, Timothy, T. Silver Spring, MD 20906 (US) BERGER, Mitchel, S. Mercer Island, WA 98040 (US) RAPOPORT, Stanely Washington, DC 20016 (US) ALI-OSMAN, Francis Sugarland, TX 77479 (US) SHETTY, H., Umesha San Mateo, CA 94404 (US)

(74)	Representative: Davies, Jonathan Mark
	Reddie & Grose 16 Theobalds Road London WC1X 8PL London WC1X 8PL (GB)

(54)	BRANCHED ALKYL ESTERS OF 4-BIS (CHLOROETHYL) AMINOPHENYL-ALKYL CARBOXYLIC ACIDS FOR TREATMENT OF PRIMARY AND METASTATIC TUMORS OF THE LYMPHATIC SYSTEM, AND OF CANCERS OF THE BREAST AND OVARIES