(19)
(11)
EP 0 514 501 A1
(12)
(43)
Date of publication:
25.11.1992
Bulletin 1992/48
(21)
Application number:
91908772.0
(22)
Date of filing:
07.02.1991
(51)
International Patent Classification (IPC):
C12N
15/
09
( . )
C12Q
1/
68
( . )
(86)
International application number:
PCT/US1991/000858
(87)
International publication number:
WO 1991/012343
(
22.08.1991
Gazette 1991/19)
(84)
Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE
(30)
Priority:
07.02.1990
US 19900477260
(71)
Applicant:
F. HOFFMANN-LA ROCHE AG
CH-4002 Basel (CH)
(72)
Inventors:
MCCORMICK, Francis, P.
Berkeley, CA 94707 (US)
LYONS, John, F.
Walnut Creek, CA 94596 (US)
(74)
Representative:
Notegen, Eric-André, et al
Grenzacherstrasse 124 Postfach 3255
CH-4002 Basel
CH-4002 Basel (CH)
(54)
DETECTION OF POINT MUTATIONS IN GENES ENCODING GTP BINDING PROTEINS