(19)
(11) EP 0 514 501 A1

(12)

(43) Date of publication:
25.11.1992 Bulletin 1992/48

(21) Application number: 91908772.0

(22) Date of filing: 07.02.1991
(51) International Patent Classification (IPC): 
C12N 15/ 09( . )
C12Q 1/ 68( . )
(86) International application number:
PCT/US1991/000858
(87) International publication number:
WO 1991/012343 (22.08.1991 Gazette 1991/19)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE

(30) Priority: 07.02.1990 US 19900477260

(71) Applicant: F. HOFFMANN-LA ROCHE AG
CH-4002 Basel (CH)

(72) Inventors:
  • MCCORMICK, Francis, P.
    Berkeley, CA 94707 (US)
  • LYONS, John, F.
    Walnut Creek, CA 94596 (US)

(74) Representative: Notegen, Eric-AndrĂ©, et al 
Grenzacherstrasse 124 Postfach 3255
CH-4002 Basel
CH-4002 Basel (CH)

   


(54) DETECTION OF POINT MUTATIONS IN GENES ENCODING GTP BINDING PROTEINS