(19)

(11)

EP 0 516 732 A1

(12)

(43) Date of publication: 09.12.1992 Bulletin 1992/50 (21) Application number: 91905331.0 (22) Date of filing: 19.02.1991

(51) International Patent Classification (IPC):  A61B 8/ 00( . ) A61K 49/ 00( . ) B01J 13/ 20( . ) A61K 9/ 50( . ) A61K 49/ 22( . ) (86) International application number: PCT/GB1991/000247 (87) International publication number: WO 1991/012823 (05.09.1991 Gazette 1991/21)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IT LI LU NL SE (30) Priority: 20.02.1990 GB 19900003821 (71) Applicant: Delta Biotechnology Limited Nottingham NG7 1FD (GB)	(72) Inventors: ILLUM, Lisbeth Nottingham NG7 1BA (GB) WASHINGTON, Clive Nottingham NG9 7BT (GB) (74) Representative: Bassett, Richard Simon, et al  ERIC POTTER & CLARKSON St. Mary's Court St. Mary's Gate Nottingham NG1 1LE Nottingham NG1 1LE (GB)