ANTIBODY CONSTRUCTS WITH ENHANCED BINDING AFFINITY - Patent 0517754

(19)

(11)

EP 0 517 754 A1

(12)

(43)	Date of publication:
	16.12.1992 Bulletin 1992/51

(21)	Application number: 91904780.0

(22)	Date of filing: 30.01.1991

(51)

International Patent Classification (IPC):

C12N 15/ 09^{( . )}
A61K 38/ 22^{( . )}
A61K 51/ 00^{( . )}
C07K 1/ 113^{( . )}
C07K 14/ 495^{( . )}
C07K 14/ 54^{( . )}
C07K 16/ 00^{( . )}
C07K 19/ 00^{( . )}
C12R 1/ 91^{( . )}

A61K 38/ 00^{( . )}
A61K 39/ 395^{( . )}
A61P 35/ 00^{( . )}
C07K 14/ 485^{( . )}
C07K 14/ 52^{( . )}
C07K 14/ 55^{( . )}
C07K 16/ 46^{( . )}
C12P 21/ 08^{( . )}

(86)	International application number:
	PCT/US1991/000633

(87)	International publication number:
	WO 1991/013166 (05.09.1991 Gazette 1991/21)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IT LI LU NL SE

(30)

Priority:

02.03.1990 US 19900488297

(71)	Applicant: Abbott Biotech, Inc.
	Needham Heights Massachusetts 02194 (US)

(72)	Inventor:
	GILLIES, Stephen, D. Hingham, MA 02403 (US)

(74)	Representative: Holdcroft, James Gerald, Dr., et al
	Graham Watt & Co., Riverhead Sevenoaks, Kent TN13 2BN Sevenoaks, Kent TN13 2BN (GB)

(54)	ANTIBODY CONSTRUCTS WITH ENHANCED BINDING AFFINITY