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(11)

EP 0 518 930 A1

(12)

(43) Date of publication: 23.12.1992 Bulletin 1992/52 (21) Application number: 91905452.0 (22) Date of filing: 01.03.1991

(51) International Patent Classification (IPC):  A61K 31/ 715( . ) C08B 37/ 16( . ) A61K 47/ 48( . ) (86) International application number: PCT/AU1991/000071 (87) International publication number: WO 1991/013100 (05.09.1991 Gazette 1991/21)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IT LI LU NL SE (30) Priority: 02.03.1990 AU 19900008899 08.03.1990 AU 19900008993 28.03.1990 AU 19900009344 29.03.1990 AU 19900009373 23.04.1990 AU 19900009756 03.08.1990 AU 19900001538 16.08.1990 AU 19900001755 12.09.1990 AU 19900002269 29.11.1990 AU 19900003596 30.11.1990 AU 19900003624 21.01.1991 AU 19910004284 14.02.1991 AU 19910004603 27.02.1991 AU 19910004856 (71) Applicant: AUSTRALIAN COMMERCIAL RESEARCH & DEVELOPMENT LIMITED Brisbane, QLD 4000 (AU)

(72) Inventors: COATES, John, Hewlett North Adelaide, S.A. 5006 (AU) EASTON, Christopher, John Bellevue Heights, S.A. 5050 (AU) LINCOLN, Stephen, Frederick Stonyfell, S.A. 5066 (AU) VAN EYK, Stephen John, Z K Kunststofflab. B L D-6700 Ludwigudwigshafen (DE) MAY, Bruce, Lindley Tranmere, S.A. 5073 (AU) WILLIAMS, Michael, Lloyd Brompton, S.A. 5007 (AU) BROWN, Susan, Elizabeth Enfield, S.A. 5085 (AU) LEPORE, Angelo Magill, S.A. 5072 (AU) LIAO, Ming-Long Montmorency, VIC 3094 (AU) LUO, Yin Morphettville, S.A. 5043 (AU) MACOLINO, Vilma Enfield, S.A. 5085 (AU) SCHIESSER, Deborah, Susanne Reno, NV 89503 (US) WHALLAND, Craig Bernard Parafield Airport, S.A. 5106 (AU) McKENZIE, Ian, S., C. West Brunswick, VIC 3055 (AU) (74) Representative: Schumann, Klaus (DE)  Patentanwälte Grünecker, Kinkeldey, Stockmair & Partner Maximilianstrasse 58 D-80538 München D-80538 München (DE)