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(11)

EP 0 521 977 A1

(12)

(43) Date of publication: 13.01.1993 Bulletin 1993/02 (21) Application number: 91906843.0 (22) Date of filing: 27.03.1991

(51) International Patent Classification (IPC):  A61K( . ) A61K 49/ 04( . ) A61K 51/ 04( . ) A61K 49/ 00( . ) A61K 51/ 02( . ) C07F 11/ 00( . ) (86) International application number: PCT/EP1991/000587 (87) International publication number: WO 1991/014460 (03.10.1991 Gazette 1991/23)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IT LI LU NL SE (30) Priority: 28.03.1990 GB 19900006977 (60) Divisional application: 94203047.9 / 0645146 (71) Applicant: NYCOMED IMAGING AS N-0401 Oslo 4 (NO)

(72) Inventors: BERG, Arne N-1310 Blommenholm (NO) ALMEN, Torsten S-217 74 Malmö (SE) KRAUTWURST, Klaus, Dieter N-1320 Stabekk (NO) KIM, Sook-Hui Mountain View, CA 94040 (US) RONGVED, Pal N-1457 Hellvik (NO) KLAVENESS, Jo N-0276 Oslo 2 (NO) DUGSTAD, Harald N-0576 Oslo 5 (NO) (74) Representative: Cockbain, Julian, Dr., et al  Frank B. Dehn & Co. Imperial House 15-19 Kingsway London WC2B 6UZ London WC2B 6UZ (GB)