(19)
(11) EP 0 522 000 A1

(12)

(43) Date of publication:
13.01.1993 Bulletin 1993/02

(21) Application number: 91907085.0

(22) Date of filing: 25.03.1991
(51) International Patent Classification (IPC): 
A61K 31/ 16( . )
A61K 31/ 27( . )
A61K 31/ 34( . )
A61K 31/ 415( . )
A61K 31/ 47( . )
A61P 9/ 10( . )
A61P 17/ 00( . )
A61P 25/ 04( . )
A61P 27/ 14( . )
A61P 29/ 00( . )
A61P 37/ 08( . )
C07C 259/ 06( . )
C07D 213/ 30( . )
C07D 215/ 42( . )
C07D 307/ 82( . )
A61K 31/ 17( . )
A61K 31/ 275( . )
A61K 31/ 343( . )
A61K 31/ 4184( . )
A61P 9/ 08( . )
A61P 11/ 00( . )
A61P 25/ 00( . )
A61P 27/ 02( . )
A61P 27/ 16( . )
A61P 37/ 00( . )
A61P 43/ 00( . )
C07C 275/ 64( . )
C07D 215/ 14( . )
C07D 235/ 12( . )
(86) International application number:
PCT/US1991/002010
(87) International publication number:
WO 1991/014674 (03.10.1991 Gazette 1991/23)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE

(30) Priority: 27.03.1990 US 19900500153
27.03.1990 US 19900500179

(71) Applicant: SMITHKLINE BEECHAM CORPORATION
King of Prussia, PA 19406 (US)

(72) Inventors:
  • ADAMS, Jerry, Leroy
    Wayne, PA 19087 (US)
  • GARIGIPATI, Ravi, Shanker
    Wayne, PA 19087 (US)
  • GRISWOLD, Don, Edgar
    North Wales, PA 19454 (US)
  • SCHMIDT, Stanley, James
    Chester Springs, PA 19425 (US)

(74) Representative: Thompson, Clive Beresford, et al 
SmithKline Beecham plc Corporate Intellectual Property SB House Great West Road
Brentford, Middlesex TW8 9BD
Brentford, Middlesex TW8 9BD (GB)

   


(54) 5-LIPOXYGENASE INHIBITORS