SUBSTITUTED PYRIMIDINES, PYRIMIDINONES AND PYRIDOPYRIMIDINES - Patent 0522038

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(11)

EP 0 522 038 A1

(12)

(43)	Date of publication:
	13.01.1993 Bulletin 1993/02

(21)	Application number: 91907332.0

(22)	Date of filing: 27.03.1991

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International Patent Classification (IPC):

A61K 31/ 505^{( . )}
A61P 27/ 02^{( . )}
C07D 239/ 28^{( . )}
C07D 239/ 38^{( . )}
C07D 239/ 46^{( . )}
C07D 401/ 12^{( . )}
C07D 403/ 12^{( . )}
C07F 9/ 6512^{( . )}
C07F 9/ 6524^{( . )}

A61P 9/ 12^{( . )}
C07D 239/ 26^{( . )}
C07D 239/ 36^{( . )}
C07D 239/ 42^{( . )}
C07D 401/ 10^{( . )}
C07D 403/ 10^{( . )}
C07D 471/ 04^{( . )}
C07F 9/ 6518^{( . )}

(86)	International application number:
	PCT/US1991/001951

(87)	International publication number:
	WO 1991/015209 (17.10.1991 Gazette 1991/24)

(84)	Designated Contracting States:
	CH DE FR GB IT LI NL

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Priority:

30.03.1990 US 19900501580

(71)	Applicant: MERCK & CO. INC.
	Rahway New Jersey 07065-0900 (US)

(72)	Inventors:
	ALLEN, Eric, E. Edison, NJ 08817 (US) GREENLEE, William, J. Teaneck, NJ 07666 (US) MacCOSS, Malcolm Freehold, NJ 07728 (US) PATCHETT, Arthur, A. Westfield, NJ 07090 (US)

(74)	Representative: Barrett-Major, Julie Diane, et al
	Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road Harlow Essex CM20 2QR Harlow Essex CM20 2QR (GB)

(54)	SUBSTITUTED PYRIMIDINES, PYRIMIDINONES AND PYRIDOPYRIMIDINES