(19)

(11)

EP 0 523 037 A1

(12)

(43) Date of publication: 20.01.1993 Bulletin 1993/03 (21) Application number: 90907852.0 (22) Date of filing: 30.03.1990

(51) International Patent Classification (IPC):  A61K 31/ 16( . ) A61K 47/ 48( . ) (86) International application number: PCT/US1990/001768 (87) International publication number: WO 1991/015215 (17.10.1991 Gazette 1991/24)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB IT LI LU NL SE (71) Applicant: BIOMEDICAL FRONTIERS, INC. Minneapolis Minnesota 55414 (US)	(72) Inventors: HEDLUND, Bo, Erik New Brighton, MN 55112 (US) HALLAWAY, Philip, E. Minneapolis, MN 55408 (US) (74) Representative: Seaborn, George Stephen  c/o Edward Evans & Co. Chancery House 53-64 Chancery Lane London WC2A 1SD London WC2A 1SD (GB)