3-NAPHTHYL-3-CARBOXYALKYLTHIO OR OXY SUBSTITUTED ALKANOIC ACID LEUKOTRIENE ANTAGONISTS - Patent 0527175

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EP 0 527 175 A1

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(43)	Date of publication:
	17.02.1993 Bulletin 1993/07

(21)	Application number: 91908637.0

(22)	Date of filing: 26.04.1991

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International Patent Classification (IPC):

A61K 31/ 16^{( . )}
A61K 31/ 185^{( . )}
A61K 31/ 215^{( . )}
A61K 31/ 275^{( . )}
A61K 31/ 341^{( . )}
A61K 31/ 425^{( . )}
A61P 11/ 08^{( . )}
C07C 45/ 46^{( . )}
C07C 45/ 68^{( . )}
C07C 59/ 66^{( . )}
C07C 69/ 76^{( . )}
C07C 261/ 04^{( . )}
C07C 323/ 56^{( . )}
C07D 233/ 64^{( . )}
C07D 277/ 22^{( . )}
C07D 277/ 26^{( . )}

A61K 31/ 18^{( . )}
A61K 31/ 19^{( . )}
A61K 31/ 27^{( . )}
A61K 31/ 34^{( . )}
A61K 31/ 415^{( . )}
A61K 31/ 426^{( . )}
A61P 43/ 00^{( . )}
C07C 45/ 56^{( . )}
C07C 45/ 71^{( . )}
C07C 59/ 68^{( . )}
C07C 69/ 94^{( . )}
C07C 317/ 44^{( . )}
C07D 213/ 00^{( . )}
C07D 257/ 04^{( . )}
C07D 277/ 24^{( . )}
C07D 307/ 38^{( . )}

(86)	International application number:
	PCT/US1991/002889

(87)	International publication number:
	WO 1991/017149 (14.11.1991 Gazette 1991/26)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IT LI LU NL SE

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Priority:

01.05.1990 US 19900518583

(71)	Applicant: SMITHKLINE BEECHAM CORPORATION
	King of Prussia, PA 19406 (US)

(72)	Inventors:
	FRAZEE, James, Simpson Sewell, NJ 08080 (US) GLEASON, John, Gerald Downingtown, PA 19335 (US) HALL, Ralph, Floyd Villanova, PA 19085 (US) UZINSKAS, Irene, Nijole Villanova, PA 19085 (US)

(74)	Representative: Giddings, Peter John, Dr.
	SmithKline Beecham plc Corporate Intellectual Property SB House Great West Road Brentford, Middlesex TW8 9BD Brentford, Middlesex TW8 9BD (GB)

(54)	3-NAPHTHYL-3-CARBOXYALKYLTHIO OR OXY SUBSTITUTED ALKANOIC ACID LEUKOTRIENE ANTAGONISTS