(19)
(11) EP 0 527 764 A1

(12)

(43) Date of publication:
24.02.1993 Bulletin 1993/08

(21) Application number: 91907465.0

(22) Date of filing: 05.04.1991
(51) International Patent Classification (IPC): 
A61K 38/ 55( . )
A61P 17/ 00( . )
A61P 29/ 00( . )
A61P 43/ 00( . )
C07K 1/ 113( . )
C07K 5/ 08( . )
A61K 38/ 00( . )
A61P 3/ 08( . )
A61P 25/ 00( . )
A61P 35/ 00( . )
C07K 1/ 02( . )
C07K 5/ 06( . )
C07K 14/ 81( . )
(86) International application number:
PCT/GB1991/000538
(87) International publication number:
WO 1991/015507 (17.10.1991 Gazette 1991/24)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE

(30) Priority: 10.04.1990 GB 19900008078

(71) Applicant: Beecham Group p.l.c.
Brentford Middlesex TW8 9BD (GB)

(72) Inventors:
  • MARKWELL, Roger Edward, SmithKline Beecham
    Harlow, Essex CM19 5AD (GB)
  • WARD, Robert William, SmithKline Beecham
    Harlow, Essex CM19 5AD (GB)
  • RATCLIFFE, Steven John, SmithKline Beecham
    Harlow, Essex CM19 5AD (GB)

(74) Representative: Giddings, Peter John, Dr., et al 
SmithKline Beecham plc Corporate Intellectual Property SB House Great West Road
Brentford, Middlesex TW8 9BD
Brentford, Middlesex TW8 9BD (GB)

   


(54) PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY