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<ep-patent-document id="EP92307577B8W1" file="EP92307577W1B8.xml" lang="en" country="EP" doc-number="0528686" kind="B8" correction-code="W1" date-publ="20040114" status="c" dtd-version="ep-patent-document-v1-1">
<SDOBI lang="en"><B000><eptags><B001EP>ATBECHDEDKESFRGBGRITLILUNLSEMCPTIE..............................................</B001EP><B005EP>J</B005EP><B007EP>DIM350 (Ver 2.1 Jan 2001)
 2999001/0</B007EP><B070EP>The file contains technical information submitted after the application was filed and not included in this specification</B070EP></eptags></B000><B100><B110>0528686</B110><B120><B121>CORRECTED EUROPEAN PATENT SPECIFICATION</B121></B120><B130>B8</B130><B132EP>B1</B132EP><B140><date>20040114</date></B140><B150><B151>W1</B151><B153>22</B153><B155><B1551>DE</B1551><B1552>Bibliographie</B1552><B1551>EN</B1551><B1552>Bibliography</B1552><B1551>FR</B1551><B1552>Bibliographie</B1552></B155></B150><B190>EP</B190></B100><B200><B210>92307577.4</B210><B220><date>19920819</date></B220><B240><B241><date>19941004</date></B241><B242><date>19950725</date></B242></B240><B250>en</B250><B251EP>en</B251EP><B260>en</B260></B200><B300><B310>23076991</B310><B320><date>19910819</date></B320><B330><ctry>JP</ctry></B330><B310>22352092</B310><B320><date>19920731</date></B320><B330><ctry>JP</ctry></B330></B300><B400><B405><date>20040114</date><bnum>200403</bnum></B405><B430><date>19930224</date><bnum>199308</bnum></B430><B450><date>20031105</date><bnum>200345</bnum></B450><B451EP><date>20020111</date></B451EP><B480><date>20040114</date><bnum>200403</bnum></B480></B400><B500><B510><B516>7</B516><B511> 7C 12N  15/62   A</B511><B512> 7C 12P  21/02   B</B512><B512> 7C 12N  15/16   B</B512></B510><B540><B541>de</B541><B542>Verfahren zur Herstellung von Peptiden</B542><B541>en</B541><B542>Process for producing peptides</B542><B541>fr</B541><B542>Procédé pour la production de peptides</B542></B540><B560><B561><text>EP-A- 0 281 418</text></B561><B562><text>JOURNAL OF BIOCHEMISTRY vol. 102, no. 1 , July 1987 , TOKYO JP pages 111 - 122 SAITO ET AL. 'Bacterial synthesis of recombinant alpha-Human Atrial Natriuretic polypeptide'</text></B562><B562><text>GENE. vol. 32 , 1984 , AMSTERDAM NL pages 321 - 327 SMITH ET AL. 'Chemical synthesis and cloning of a poly(arginine)-coding gene fragment designated to aid polypeptide purification'</text></B562><B562><text>LI ET AL.: 'Characterization of mutants affecting the KRK sequence in the C-terminal domain of lac repressor' JOURNAL OF BIOLOGICAL CHEMISTRY vol. 270, no. 18, 05 May 1995, pages 10640 - 10649</text></B562><B562><text>PARSELL ET AL.: 'The structural stability of a protein is an important determinant of its proteolytic susceptibility in E. coli' JOURNAL OF BIOLOGICAL CHEMISTRY vol. 264, no. 13, 05 May 1989, pages 7590 - 7595</text></B562><B562><text>TAJIMA ET AL.: 'High-level synthesis in E.coli of recombinant human calcitonin: Collagenase claevage of the fusion protein and peptidylglycine alpha-amidation' JOURNAL OF FERMENTATION AND BIOENGINEERING vol. 72, no. 5, 1991, pages 362 - 367</text></B562></B560><B590><B598>NONE</B598></B590></B500><B700><B720><B721><snm>Yabuta, Masayuki</snm><adr><str>743-88, Kokuwabara</str><city>Tatebayashi-shi,
Gunma</city><ctry>JP</ctry></adr></B721><B721><snm>Suzuki, Yuji</snm><adr><str>Soler Heights Watarase 603,
308, Asakura-cho</str><city>Ashikaga-shi,
Tochigi</city><ctry>JP</ctry></adr></B721><B721><snm>Ohsuye, Kazuhiro</snm><adr><str>10-12, Akeno,
Ohra-cho</str><city>Ohra-gun,
Gunma</city><ctry>JP</ctry></adr></B721><B721><snm>Oshima, Takehiro</snm><adr><str>15-2-606, Tanaka-cho</str><city>Ashikaga-shi,
Tochigi</city><ctry>JP</ctry></adr></B721><B721><snm>Onai, Seiko</snm><adr><str>1424, Tsunatorihonmachi</str><city>Isesaki-shi,
Gunma</city><ctry>JP</ctry></adr></B721><B721><snm>Magota, Koji</snm><adr><str>6-10-1-611, Magami-cho</str><city>Takatsuki-shi,
Osaka</city><ctry>JP</ctry></adr></B721><B721><snm>Tanaka, Shoji</snm><adr><str>4-9-1, Shiomi-cho</str><city>Ashiya-shi,
Hyogo</city><ctry>JP</ctry></adr></B721></B720><B730><B731><snm>Daiichi Suntory Pharma Co., Ltd.</snm><iid>04380801</iid><irf>5072665</irf><adr><str>7-2, Kojimachi 5-chome, Chiyoda-ku</str><city>Tokyo</city><ctry>JP</ctry></adr></B731></B730><B740><B741><snm>Stoner, Gerard Patrick</snm><sfx>et al</sfx><iid>00059901</iid><adr><str>MEWBURN ELLIS
York House
23 Kingsway</str><city>London WC2B 6HP</city><ctry>GB</ctry></adr></B741></B740></B700><B800><B840><ctry>AT</ctry><ctry>BE</ctry><ctry>CH</ctry><ctry>DE</ctry><ctry>DK</ctry><ctry>ES</ctry><ctry>FR</ctry><ctry>GB</ctry><ctry>GR</ctry><ctry>IE</ctry><ctry>IT</ctry><ctry>LI</ctry><ctry>LU</ctry><ctry>MC</ctry><ctry>NL</ctry><ctry>PT</ctry><ctry>SE</ctry></B840><B880><date>19940406</date><bnum>199414</bnum></B880></B800></SDOBI>
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